![]() ![]() In 2018, the World Health Organization (WHO) established the “Blueprint priority disease list”, identifying viruses such as Ebola, Lassa fever, Middle East Respiratory Syndrome (MERS), and Nipah fever as significant threats to international biosecurity 1. The burden of emerging infectious diseases has significantly increased over the last decades and is recognized as a major global health concern. Future studies should investigate whether CoVs detected in these bats have a potential for spillover in other hosts. These results highlight that strong variation between islands does exist and is associated with the composition of the bat species community on each island. Phylogenetic analyses revealed a large diversity of α- and β-CoVs and a strong signal of co-evolution between CoVs and their bat host species, with limited evidence for host-switching, except for bat species sharing day roost sites. In total, 88 bats (8.7%) tested positive for coronaviruses, with higher prevalence in Mozambican bats (20.5% ± 4.9%) as compared to those sampled on islands (4.5% ± 1.5%). In this study, we tested 1,013 bats belonging to 36 species from Mozambique, Madagascar, Mauritius, Mayotte, Reunion Island and Seychelles, based on molecular screening and partial sequencing of the RNA-dependent RNA polymerase gene. ![]() The islands of the Western Indian Ocean are identified as a major biodiversity hotspot, with more than 50 bat species. Bats are also major hosts for biological agents responsible for zoonoses, such as coronaviruses (CoVs). Affordability: The software is highly affordable, making it accessible to even the smallest research teams.Bats provide key ecosystem services such as crop pest regulation, pollination, seed dispersal, and soil fertilization. Scalability: The software is designed to scale up and handle large datasets, making it suitable for high-throughput projects. Security: The software is secure and encrypted, providing users with peace of mind that their data is safe. Open-source: The software is open-source, allowing users to customize the software to their specific needs. Automated reports: The software can generate automated reports with key results, making it easy to communicate findings. Reference genome support: The software supports a wide range of reference genomes, allowing users to compare their data with a wide range of species. Robust statistics: The software includes a wide range of statistical tools for analyzing and interpreting data. Cloud-based: The software is cloud-based, allowing users to access the tools from anywhere and collaborate in real-time with colleagues. Advanced visualizations: The software includes advanced visualization tools such as heatmaps and 3D visualizations for exploring results. Flexible data formats: The software supports a wide range of data formats, allowing users to easily integrate data from different sources and platforms. ![]() Easy-to-use graphical interface: The graphical user interface of the software makes it easy to use and understand even for non-specialists. Automated analysis pipelines: CLC Genomics Workbench comes with pre-defined pipelines for a range of genomic analysis tasks such as variant calling, expression analysis, and de novo assembly. It is a comprehensive tool that enables users to analyze, visualize, and interpret large volumes of biological data.ĬLC Genomics Workbench allows users to quickly and intuitively perform comprehensive bioinformatics analysis on large datasets. The CLC Genomics Workbench is a powerful next-generation sequence analysis software platform designed to meet the needs of today's genomics research. ![]()
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